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AssigneesIndustry-Academic Cooperation Foundation Gyeongsang National University, Gwangju Institute of Science and Technology
InventorsKi Hun PARK, Soo Hyun EOM, Young Bae RYU, Jung Keun CHO
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The present invention relates to a composition for suppressing neuraminidase activity comprising a geranylated flavonoid derived from Paulownia tomentosa as an active ingredient. The Paulownia tomentosa extract and the geranylated flavonoid isolated therefrom exhibit an effect in significantly suppressing neuraminidase, which is an enzyme that plays an important role in the occurrence of pathogenic viral and bacterial infections and of the inflammation that accompanies such infection, and thus the Paulownia tomentosa extract or the geranylated flavonoid isolated therefrom can advantageously be used as an active ingredient in a composition for inhibiting neuraminidase activity.
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A method for inhibiting neuraminidase activity, comprising administering administering a pharmaceutically effective amount of an extract of Paulownia tomentosa or a fraction thereof to an individual.
A method for inhibiting neuraminidase activity, comprising administering a pharmaceutically effective amount of a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof to an individual.
A method for treating viral or bacterial inflammatory diseases comprising administering a pharmaceutically effective amount of a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.