Compositions and methods for improving cognitive function
AssigneeAbbott Laboratories
InventorsAlejandro Barranco Perez, Enrique Vazquez Hernandez, Maria Ramirez Gonzalez, Ricardo Rueda Cabrera
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Abstract
Compositions including a combination of a source of choline, a source of magnesium, and a source of L-tryptophan are provided for improving cognitive performance in a subject. The compositions may improve a cognitive impairment and/or brain dysfunction associated with age-related cognitive decline or cognitive decline resulting from a neurodegenerative disease. The compositions may also be effective in improving memory acquisition, memory retention, and recall.
Claims21
1-29. (canceled)
A composition for maintaining or improving cognition in a subject, the composition comprising:
- a source of choline in an amount sufficient to provide 0.4 to 8 grams of choline per day;
- a source of magnesium in an amount sufficient to provide 0.2 to 3 grams of magnesium per day;
- a source of threonate;
- and a source of L-tryptophan.
A composition for maintaining or improving cognition in a subject, the composition comprising:
- 0.1 to 40 weight percent of a source of choline;
- 0.1 to 30 weight percent of magnesium threonate;
- and a source of L-tryptophan, wherein the weight percentages are of the total solids of the composition.
A method of treating or preventing a neurodegenerative disease or condition, the method comprising:
- administering an effective amount of glycerophosphocholine;
- an effective amount of a source of magnesium;
- and an effective amount of a source of L-tryptophan to a subject, wherein the effective amounts maintain or stimulate brain function in the subject and thereby maintain or improve cognition of the subject.
Dependencies are inferred from the claim text.