Filamentary devices for treatment of vascular defects

A method for treating a cerebral aneurysm, comprising the steps of:

• providing an implant comprising woven braided mesh, the implant having a proximal end with a hub, a distal end, and a longitudinal axis extending from the proximal end to the distal end,
• wherein the implant has a distal region, a proximal region, and a transition region that lies substantially perpendicular to the longitudinal axis of the implant and extends between the distal and proximal regions;
• wherein the implant has an expanded configuration when deployed, the expanded implant having a region of maximum diameter that extends from a proximal portion of the distal region through the transition region and to a distal portion of the proximal region,
• wherein a diameter of a pore within the proximal portion of the distal region is larger than all pores in the distal portion of the proximal region;
• advancing the implant in the low profile radially constrained state within a microcatheter to a region of interest within a cerebral artery;
• deploying the implant within the cerebral aneurysm, wherein the distal and proximal permeable shells expand to their expanded shapes;
• and
• withdrawing the microcatheter from the region of interest after deploying the implant.