Omega-3 compositions, dosage forms, and methods of use
AssigneeMarine Ingredients, LLC
InventorsOlav Sandnes, Bruce A. Miller, Jorn Dyerberg, Steen Stender
Life of this patent
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Abstract
Omega-3 compositions, dosage forms, and methods of use are disclosed herein. The omega-3 compositions and dosage forms disclosed herein may comprise DHA and EPA at a ratio of about 5:2. The omega-3 compositions and dosage forms disclosed herein may comprise re-esterified triglycerides. Methods of treatment using the compositions and dosage forms are also disclosed.
Claims20
A composition comprising:
- a marine oil comprising fatty acids, including omega-3 polyunsaturated fatty acids (PUFAs), wherein 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid (DHA) and 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid (EPA) comprise at least a portion of the PUFAs and a ratio of DHA to EPA is about 3:2 to about 4:1.
A dosage form comprising:
- a marine oil comprising fatty acids, including omega-3 polyunsaturated fatty acids (PUFAs), wherein 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid (DHA) and 5Z,8Z, 11Z,14Z,17Z-eicosapentaenoic acid (EPA) comprise at least a portion of the PUFAs, and wherein an amount of DHA is at least about 450 mg and an amount of EPA is at least about 150 mg.
A method of reducing the risk of mortality in a subject, extending the life of a subject, reducing the risk of coronary heart disease (CHD) in a subject, reducing the risk of sudden cardiac death (SDC) in a subject, reducing the risk of cardiac arrest in a subject, treating hypertriglyceridemia in a subject, reducing triglycerides in a subject's blood, increasing an omega-3 index in red blood cells of a subject, reducing the resting heart rate of a subject, increasing high-density lipoprotein cholesterol (HDL-c) in a subject, reducing non-high-density lipoprotein cholesterol (non-HDL-c) in a subject, reducing total cholesterol in a subject, reducing Apolipoprotein B (Apo-B) in a subject's blood, reducing systolic blood pressure in a subject, or reducing diastolic blood pressure in a subject, the method comprising:
- administering a composition comprising a marine oil comprising fatty acids, including omega-3 polyunsaturated fatty acids (PUFAs), wherein 4Z,7Z, 10Z,13Z,16Z,19Z-docosahexaenoic acid (DHA) and 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid (EPA) comprise at least a portion of the PUFAs and a ratio of DHA to EPA is about 3:2 to about 4:1.
Dependencies are inferred from the claim text.