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US 2016/0243025 A1Published application
Topical Formulation for Pain Relief
OwnerHelene Bertrand, Marylene Kyriazisinventors
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Abstract
Described herein are topical pain compositions comprising between 15 and 90% mannitol, for use in the treatment of pain, itch and other cutaneous nerve conditions. The resulting compositions may be in the form of creams, gels, lotions, ointments, foams, suppositories, and sprays.
Claims20
A method of treating conditions involving cutaneous nerves, the method comprising:
- preparing a topical composition comprising between 15% and 90% mannitol by weight, and at least one excipient, the excipient comprising at least one emulsifier;
- wherein the emulsifier is at least one of the group consisting of a polyethylene glycol stearate, a glycol stearate, a glyceryl stearate, cetearyl alcohol and ceteareth 20, methylcellulose, Cetamacrogol 1000, and lecithin;
- and
- applying the topical composition onto skin.
1 more element
A method of treating conditions involving cutaneous nerves, the method comprising:
- preparing a topical composition comprising between 15% and 90% mannitol by weight, and at least one excipient;
- the at least one excipient comprising an emollient;
- wherein the emollient is at least one of cetostearyl alcohol, cetyl alcohol, isopropyl palmitate, caprylic/capric triglyceride, PPG2 myristyl ether propionate, dimethicone, methicone, petrolatum, lanolin, and mineral oil;
- and
- applying the topical composition onto skin.
2 more elements
A method of treating conditions involving cutaneous nerves, the method comprising:
- preparing a topical pain relief composition comprising between 15 and 90% mannitol by weight;
- between 0.25% and 20.0% menthol by weight;
- and at least one excipient, the at least one excipient comprising an organogelator;
- the organogelator is at least one of 4-tertbutyl-1-aryl cyclohecanols derivatives, polymeric (e.g. poly(ethylene glycol), polycarbonate, polyesters, and poly(alkylene), Gemini gelators (e.g. N-Iauroyl-L-Iysine ethyl ester), Boc-Ala(I)Aib(2)-β-Ala(3)-OMe (synthetic tripeptide), and low molecular weight gelators (e.g. fatty acids and n-alkanes).
1 more element
Dependencies are inferred from the claim text.