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US 2016/0237444 A1Published application
Engineering of Hydrocarbon Metabolism in Yeast
AssigneeBiopetrolia AB
InventorsJens Nielsen, Verena Siewers, Paulo Alexandre Goncalves Teixeira, Yongjin Zhou, Nicolaas A. A. Buijs, Florian David
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Abstract
The present invention relates to the development of genetically engineered yeasts that can produce hydrocarbons in a controllable and economic fashion. More specifically the invention relates to the production of liquid alkanes and alkenes that can be used for liquid transportation fuels, specialty chemicals, or feed stock for further chemical conversion.
Claims30
A yeast, wherein
- said yeast lacks a gene encoding hexadecanal dehydrogenase (HFD1) or comprises a disrupted gene encoding HFD1;
- and
- said yeast comprises at least one heterologous gene encoding an enzyme involved in a pathway of producing hydrocarbons.
A method for producing hydrocarbons comprising:
- culturing a yeast lacking a gene encoding hexadecenal dehydrogenase (HFD1) or comprising a disrupted gene encoding HFD1 in culture conditions suitable for production of said hydrocarbons from said yeast;
- and
- collecting said hydrocarbons from the culture medium in which said yeast is cultured and/or from said yeast.
28-30. (canceled)
Dependencies are inferred from the claim text.