Control of Blood Vessel Physiology To Treat Skin Disorders

A method for treating an affected skin region of a patient having a skin disorder, the method comprising:

• a) applying a vasodilation composition to an affected skin region of a patient, said affected skin region exhibiting a skin disorder characterized by at least one abnormal blood vessel, wherein said blood vessel comprises a tissue architecture,
• b) waiting for a time sufficient to allow vasodilation of said at least one abnormal blood vessel in said affected skin region;
• c) non-invasively disrupting the tissue architecture of said vasodilated at least one abnormal blood vessel;
• and
• d) subsequent to disrupting the tissue architecture, applying a vasoconstriction composition to the affected skin region so as to cause vasoconstriction and collapse of the at least one abnormal blood vessel.