Eye drop formulation with enhanced properties by combining sodium hyaluronate with carboxymethylcellulose
AssigneeAllergan, Inc.
InventorsBereth J. Beard, Wendy Blanda, David Marsh, Joseph G. Vehige, Peter Simmons, Haixia Liu, Steven Matsumoto
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Abstract
Embodiments described herein relate to formulations for and methods of use for eye drop formulations comprising carboxymethyl cellulose (CMC) and hyaluronic acid (HA) with an improved distribution on the cornea during blinking.
Claims29
A composition useful as an artificial tear, which comprises a mixture of Carboxymethyl cellulose and hyaluronic acid with an improved distribution on the cornea during blinking.
The method of improving the visual acuity of a person in need thereof which comprises topically administering to said person, in an effective amount, an ophthalmic composition comprising a mixture of Carboxymethyl cellulose and hyaluronic acid with an improved distribution on the cornea during blinking.
A composition useful as an artificial tear, the composition comprising from about 0.5% w/v to about 1% w/v carboxymethylcellulose sodium, about 0.1 to about 0.15% w/v sodium hyaluronate, at least one buffering agent, at least one excipient, at least one pH adjuster, and water to balance.
Dependencies are inferred from the claim text.