Device and Method for Mitral Valve Regurgitation Treatment

A method of deploying a mitral valve replacement device at a native mitral valve position in a human heart, comprising:

• providing a mitral valve replacement device comprising:
• an atrial flange defining an atrial end of the device;
• a ventricular portion defining a ventricular end of the device, the ventricular portion having a height ranging between 2 mm to 15 mm;
• an annulus support that is positioned between the atrial flange and the ventricular portion, the annulus support including a ring of anchors extending radially therefrom, with an annular clipping space defined between the atrial flange and the ring of anchors;
• a plurality of leaflet holders positioned at the atrial end of the atrial flange;
• and
• a plurality of valve leaflets secured to the leaflet holders, and positioned inside the atrial flange;
• seating the atrial flange in the atrium above a native mitral valve annulus in a human heart in a manner where the plurality of leaflets are positioned above the native annulus;
• and
• positioning the native mitral annulus and/or the native mitral valve leaflet(s) in the clipping space.