Insertable endoscopic instrument for tissue removal

An endoscopic instrument insertable within a single instrument channel of a flexible endoscope, the endoscopic instrument comprising:

• a cutting assembly configured to resect material at a site within a subject, the cutting assembly including an outer cannula and an inner cannula disposed within the outer cannula, the outer cannula defining an opening through which the material to be resected enters the cutting assembly;
• a flexible outer tubing coupled to the outer cannula and configured to rotate the outer cannula relative to the inner cannula, the flexible outer tubing having an outer diameter that is smaller than the instrument channel in which the endoscopic instrument is insertable;
• a flexible torque component comprising one of a flexible torque coil or a flexible torque rope, the flexible torque component having a portion disposed within the flexible outer tubing, the flexible torque component having a distal end coupled to the inner cannula, the flexible torque component configured to rotate the inner cannula relative to the outer cannula to resect the material to be resected responsive to applying torque of the flexible torque component;
• and
• an aspiration channel having an aspiration port configured to engage with a vacuum source, the aspiration channel partially defined by an inner wall of the flexible torque coil and an inner wall of the inner cannula and extending from an opening defined in the inner cannula, through the outer tubing to the aspiration port.