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AssigneeTechnicka Univerzita V Liberci
InventorsIrena Slamborova, Veronika Zajicova, Petr Exnar, Jarmila Studnickova
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The invention concerns a nanofiber structure with immobilized organic agens that consists of silica nanofibers whose surface was modified with aminoaikyialkoxysilane and of subsequently immobilized organic agens. The invention also concerns a method of preparation of the nanofiber structure with immobilized organic agens, while silica nanofibers are prepared by electrostatic spinning from the initial sol synthesized by a sol-gel method from tetraalkoxysilane, heat-treated and their the surface modified by a solution of aminoaikyialkoxysilane and organic agens is then immobilized on the modified surface of the nanofibers.
A nanofibrous structure with immobilized organic substance composed of pure silica nanofibres made by electrostatic spinning, the nanofibers have controlled dissolution in body fluids or in bioreactor and have surface modified by aminoalkylalkoxysilane with subsequently immobilized organic agent substances.
The method of production of nanofibrous structure with immobilized organic substance, wherein, from the initial sol synthesized by the sol-gel method from tetraalkoxysilane by means of electrostatic spinning the pure silica nanofibres are created, which are subsequently heat treated for controlled dissolution in body fluids or in bioreactor and then surface of nanofibres is modified by means of solution of aminoalkylalkoxysilane, after which to such modified surface of nanofibres the organic substances are immobilized.
Dependencies are inferred from the claim text.