Method for decreasing symptoms of alcohol consumption
AssigneeAlcobra Ltd.
InventorsGur Megiddo, Dalia Megiddo, Rina Yamin, Yaron Ilan, Shimon Amselem
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Abstract
The present invention relates to methods and compositions of metadoxine and physiologically compatible active derivatives thereof, and their use for decreasing symptoms of alcohol consumption as well as in the prevention of alcohol consumption related symptoms in subjects in need thereof.
Claims38
A method for decreasing or preventing symptoms or effects of alcohol consumption in a subject in need thereof, wherein said subject has not reached intoxication, comprising non-chronic administration of a composition comprising metadoxine.
A method for preventing alcohol intoxication in a subject in need thereof, wherein said subject has not reached intoxication, comprising administering a composition comprising metadoxine.
A method for reducing or eliminating blood alcohol levels in a subject in need thereof, wherein said subject has not reached intoxication, comprising administering a composition comprising metadoxine.
The method according to any one of the preceding claims, wherein said subject is or will be social drinking, session drinking or binge drinking.
The method according to any one of the preceding claims, wherein said composition is administered in a single dosage form or portion thereof.
The method of any one of the preceding claims, wherein the mode of administration is oral, sublingual, buccal, nasal, transdermal, transmucosal, rectal or subcutaneous administration.
A composition comprising metadoxine formulated for sustained or controlled release upon administration to a subject.
A composition comprising metadoxine, wherein a portion of the metadoxine is formulated for sustained release and a portion of the metadoxine is formulated for immediate release upon administration to a subject.
Use of metadoxine or a functional derivative thereof in the manufacture of a therapeutic composition for reducing or eliminating blood alcohol level.
Use of metadoxine or a functional derivative thereof in the manufacture of a therapeutic composition for decreasing or preventing symptoms or effects of alcohol consumption.
Use of metadoxine or a functional derivative thereof in the manufacture of a therapeutic composition for preventing alcohol intoxication.
Use of metadoxine or a functional derivative thereof formulated for sustained or controlled release in the manufacture of a therapeutic composition for increasing the mean tmax of metadoxine in the blood.
Dependencies are inferred from the claim text.