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US 2015/0175994 A1Published application
Heat-inactivated complement factor b compositions and methods
AssigneeWilliam Marsh Rice University
InventorNANCY A. TURNER
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Abstract
The present disclosure is directed to compositions comprising heat-inactivated complement factor B and methods of using the same to treat thrombotic or complement-mediated inflammatory disorders.
Claims18
A composition comprising a heat-inactivated complement factor B.
A method comprising administering a composition to an individual at risk for or suffering from a complement-mediated inflammatory disorder, wherein the composition comprises a heat-inactivated complement factor B.
A method for producing a therapeutic composition comprising:
- obtaining a sample containing complement factor B;
- and
- heating the sample at a temperature from about 45° C. to about 56° C. for a period of from about 5 minutes to about 20 minutes.
Dependencies are inferred from the claim text.