Protein activity modification
AssigneeImpulse Dynamics NV
InventorsBenny ROUSSO, Yuval MIKA, Shlomo BEN-HAIM, Hani N. SABBAH
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Abstract
A method of modifying tissue behavior, comprising: determining a desired modification of tissue behavior for at least one of treatment of a disease, short or long term modification of tissue behavior, assessing tissue state and assessing tissue response to stimulation; selecting an electric field having an expected effect of modifying protein activity of at least one protein as an immediate response of a tissue to the field, said expected effect correlated with said desired modification; and applying said field to said tissue.
Claims28
A method of treating a patient for chronic heart failure, comprising:
- a. selecting a patient having (i) a narrow QRS and (ii) a NYHA class of at least II;
- and
- b. applying a cardiac contractility modifying electrical therapy to a heart of said patient for at least 3 months.
Dependencies are inferred from the claim text.