Pea protein peptides with anti helicobacter pylori activity
AssigneeN.V. Nutricia
InventorsGilda Elise GEORGI, Marco Euler, Marko Mank, Andreas Hensel, Michael Niehues, Monika Klapperich, Bernd Stahl
Life of this patent
Estimating the term…
Abstract
The invention relates to a composition comprising pea protein hydrolysate for the treatment and/or prevention of infection by gastrointestinal pathogens, in particular Helicobacter pylori and/or a disease associated with infection by said gastrointestinal pathogen in mammals.
Claims9
A composition comprising a lipid, protein and carbohydrate constituent wherein the lipid constituent provides 5 to 50% of the total calories, the protein constituent provides 5 to 50% of the total calories and the carbohydrate constituent provides 15 to 90% of the total calories, wherein the protein constituent comprises:
- (i) at least one protein source consisting of pea protein hydrolysate, wherein the pea protein hydrolysate is obtained by hydrolysis with a protease in the absence of chymotrypsin and
- (ii) at least one nitrogen source selected from the group consisting of milk proteins, milk protein hydrolysate, egg proteins, egg protein hydrolysate, soy protein, soy protein hydrolysate, wheat protein, wheat protein hydrolysate, rice protein, rice protein hydrolysate, free amino acids and mixtures thereof.
A composition comprising a lipid, protein and carbohydrate constituent wherein the lipid constituent provides 5 to 50% of the total calories, the protein constituent provides 5 to 50% of the total calories and the carbohydrate constituent provides 15 to 90% of the total calories, wherein the protein constituent comprises:
- (i) at least one protein source consisting of peptides selected from the group consisting of Xaan-Asp-Phe-Leu-Glu-Asp-Ala-Phe-Asn-Val-Asn-Arg-Xaam (SEQ ID NO:
- 14) and Xaan-Glu-Leu-Ala-Phe-Pro-Gly-Ser-Ala-Gln-Glu-Val-Asp-Arg-Xaam (SEQ ID NO:
- 15), wherein each Xaa independently can be any amino acid and n and m are integers independently ranging from 0-10, and
- (ii) at least one nitrogen source selected from the group consisting of milk proteins, milk protein hydrolysate, egg proteins, egg protein hydrolysate, soy protein, soy protein hydrolysate, wheat protein, wheat protein hydrolysate, rice protein, rice protein hydrolysate, free amino acids and mixtures thereof.
A composition comprising a non-digestible oligosaccharide selected from the group consisting of trans-galactooligosaccharide, fructo-oligosaccharides, uronic acid oligosaccharide and sialyllactose and
- (a) pea protein hydrolysate, which is obtained by hydrolysis with protease other than chymotrypsin;
- and/or
- (b) at least one peptide selected from the group consisting of Xaan-Asp-Phe-Leu-Glu-Asp-Ala-Phe-Asn-Val-Asn-Arg-Xaam (SEQ ID NO:
- 14) and Xaan-Glu-Leu-Ala-Phe-Pro-Gly-Ser-Ala-Gln-Glu-Val-Asp-Arg-Xaam (SEQ ID NO:
- 15), wherein each Xaa independently can be any amino acid and n and m are integers independently ranging from 0-10.
Dependencies are inferred from the claim text.