Article of manufacture containing lyophilized leuprolide acetate
AssigneeTolmar Therapeutics, Inc.
InventorsCody L. Yarborough, Dominic G. Madril, Rajan Bawa
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Abstract
A process for lyophilizing a solution of an active agent in a container is provided. Solution of active agent is deposited into a container, the container is covered with a covering plate and placed inside a lyophilizing apparatus. Lyophilization can be conducted to dryness by radiation, convection or both. Also provided is a device made by this process, an active agent-plastic administration device (e.g., a syringe), containing an active agent in the form of lyophilized cake, and an array of such administration devices.
Claims16
(canceled)
An article of manufacture comprising first and second groups of containers, each container having at least an open top, each container containing a portion of lyophilized leuprolide acetate;
- a cover plate having an underside with protuberances attached to the underside, the protuberances being adapted to fit through the open tops of the containers and into the insides of the containers without contacting the inner surfaces of the containers, and the cover plate being juxtaposed with the containers so as to cover the containers of the first and second groups with the protuberances projecting into the insides of the containers;
- and the first group of containers being distinguished from the second group by the absence of any visible amount of lyophilized leuprolide acetate on the protuberances or corresponding cover plate undersides associated with the first group of containers.
Dependencies are inferred from the claim text.