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US 2015/0148545 A1Published application
Protein tyrosine phosphatase inhibitor, preparation method and uses thereof
AssigneeHebei University
InventorsDuqiang Luo, Jun Zhang, Zhiqin Liu
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Abstract
Disclosed in the present invention is a protein tyrosine phosphatase inhibitor. The preparation method therefor is: extracting the crude product from the Isaria Fumosorosea Wize solid or liquid fermentation broth using ethyl acetate, ethanol, methanol, or a mixed solvent of chloroform and methanol; separating the obtained extract using column chromatography on silica gel; and obtaining the target product. The inhibitor can be used to prepare pharmaceutical compositions for treating and preventing diabetes, obesity and cancers.
Claims10
A protein tyrosine phosphatase inhibitor, which is the following (a) or (b):
- (a) a compound having the following structural formula:
- (b) an isomer of the above compound or pharmaceutically acceptable derivative thereof.
Dependencies are inferred from the claim text.