Transdermal delivery patch
AssigneePhosphagenics Limited
InventorsJeremy Cottrell, Giacinto Gaetano, Mahmoud El-Tamimy, Nicholas Kennedy, Paul David Gavin
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Abstract
A composition suitable for use in a transdermal delivery patch for administration of a biologically active compound, the composition comprising a phosphate compound of tocopherol and a polymer carrier.
Claims25
A matrix layer suitable for use in a transdermal delivery patch for administration of a biologically active compound, the matrix layer comprising a mixture of a mono-tocopheryl phosphate compound and a di-tocopheryl phosphate compound and a polymer carrier wherein the polymer carrier is present in an amount within the range of about 30% w/w to about 95% w/w of the total concentration of the matrix layer.
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21-22. (canceled)
24-40. (canceled)
A method for preparing a transdermal delivery patch for administration of a bioloigically active compound comprising the steps of:
- (i) combining a polymer carrier and optional inert carrier components with a suitable solvent;
- (ii) combining (i) with a dispersion comprising a biologically active compound and a mixture of a mono-tocopheryl phosphate compound and a di-tocopheryl phosphate compound;
- (iii) stirring (ii) until complete homogenisation is achieved;
- (iv) placing the composition of (iii) in a suitable mould or casting the composition of (iii) on a surface;
- (v) drying the composition under heat.
42-43. (canceled)
Dependencies are inferred from the claim text.