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US 2015/0147767 A1Published application
Bag3 as biochemical serum and tissue marker
AssigneeBiouniversa S.R.L.
InventorMaria Caterina TURCO
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Abstract
The present invention concerns the field of diagnostic biological markers. Specifically the invention relates to anti-BAG3 antibodies for use as biological markers for the diagnosis of a pathological state. Furthermore, the invention involves specific ELISA methods and kits, for detecting and evaluating, anti-BAG3 antibodies or BAG3/antibody complexes in a biological sample.
Claims11
A method for diagnosing a pathological state, comprising the steps of:
- a. obtaining a biological sample consisting of serum, plasma, urine or saliva, and
- b. detecting the presence of an anti-BAG3 antibody or an immune complex formed from an anti-BAG3 antibody bound to soluble BAG3, and determining the presence of anti-BAG3 or BAG3 associated antibodies in the biological sample,
- wherein said pathological state is selected from the group consisting of:
- heart disease, cancer, inflammation and inflammatory related diseases of the skin, nerves, bones, blood vessels, and connective tissues, and said diagnosis is in vitro or ex vivo.
1 more element
Dependencies are inferred from the claim text.