Serological markers for cancer diagnosis using blood sample

A method for diagnosing cancer, said method comprising:

• 1) separating and concentrating glycoproteins from the sample obtained from a test subject;
• 2) preparing polypeptides by hydrolyzing the glycoproteins of step 1);
• 3) performing sequence analysis with the polypeptides of step 2);
• and
• 4) diagnosing the test subject with high risk of cancer or with cancer if the polypeptide composed of the amino acid sequence represented by SEQ ID NO:1 is detected from the sequence analysis of step 3).

A method for diagnosing cancer, said method comprising:

• 1) separating and concentrating glycoproteins from the sample obtained from a test subject;
• 2) preparing polypeptides by hydrolyzing the glycoproteins of step 1);
• 3) performing quantitative analysis with the polypeptides of step 2);
• and
• 4) diagnosing the test subject with high risk of cancer or with cancer if the polypeptide having the molecular weight of 1191.6 is detected from the quantitative analysis of step 3).

A method for diagnosing cancer, said method comprising:

• 1) measuring the expression level of Complement factor I from the sample obtained from a test subject;
• 2) selecting a subject demonstrating the increased expression level of CFI, compared with that normal control;
• and
• 3) diagnosing the selected subject of step 2) with high risk of cancer or with cancer analysis of step 2).