Suspension compositions of physiologically active phenolic compounds & methods of making and using the same
AssigneeHumanetics Corporation
InventorsDavid C. Egberg, Michael D. Kaytor, John C. Dykstra
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Abstract
The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular embodiments, the compositions described herein include suspension formulations including a physiologically active phenolic compound provided as a nanoparticulate material and dispersed within an edible lipid.
Claims36
A composition suitable for consumption by a subject, the composition comprising:
- an edible lipid;
- and
- an active material suspended within the edible lipid forming a nanoparticulate suspension, wherein the active material comprises a physiologically active phenolic compound and exhibits a particle size distribution characterized by a D (0.50) of 0.5 μm or less.
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A method for preparing an edible suspension of a physiologically active phenolic compound, the method comprising:
- providing an edible lipid;
- providing an active material comprising a physiologically active phenolic compound;
- and
- milling the active material in the presence of the edible lipid to form a nanoparticulate suspension of the active material suspended within the edible lipid, wherein the active material in the nanoparticulate suspension exhibits a particle size distribution characterized by a D(0.50) of 0.5 μm or less, and wherein milling the active material in the presence of the edible lipid comprises nanomilling the active material in a milling media that comprises the edible lipid.
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Dependencies are inferred from the claim text.