Use of g-csf dimer in the treatment of neutropenia
AssigneeGeneron (Shanghai) Corporation Ltd.
InventorsXiaoqiang YAN, Zhihua Huang, Hongzhou Yang, Bill N. Sun, Yuliang Huang
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AssigneeGeneron (Shanghai) Corporation Ltd.
InventorsXiaoqiang YAN, Zhihua Huang, Hongzhou Yang, Bill N. Sun, Yuliang Huang
Estimating the term…
This invention relates to a use of G-CSF dimer in the treatment of neutropenia. In particular, the recombinant human G-CSF of the present invention can enhance the differentiation and development of neutrophils in animal, and thus effectively reduce the severity of the severe neutropenia and shorten the time of severe neutropenia for the post-chemotherapy cancer patients. Serum half-life of G-CSF dimer of this invention is prolonged and the biological activity thereof is increased, providing a better effect in the treatment of neutropenia.
A method of treating neutropenia in an individual comprising administering to the individual a human granulocyte colony-stimulating factor (G-CSF) dimer.
(canceled)
A method of activating neutrophil precursor cells and myeloid stem cells in an individual comprising administering to the individual a human granulocyte colony-stimulating factor (G-CSF) dimer.
A method of activating mature neutrophils in an individual comprising administering to the individual a human granulocyte colony-stimulating factor (G-CSF) dimer.
Dependencies are inferred from the claim text.