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US 2015/0105475 A1Published application
Point of use generation of amyl nitrite
AssigneeSouthwest Research Institute
InventorsJoseph A. McDONOUGH, Darrel W. JOHNSTON, Paul M. THOMPSON
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Abstract
The present disclosure relates to devices and methods for the preparation of amyl nitrite formulations at a point of use location from relatively shelf-stable reagents employing acidic cationic exchange resins.
Claims19
A method for preparing amyl nitrites of the formula C5H11ONO comprising:
- forming a mixture of amyl alcohol of the formula C5H11OH with a nitrite of the formula MNO2 in an aqueous medium wherein M represents a metal cation selected from an alkali metal or alkali earth metal;
- exposing said mixture to an acidic cationic exchange resin and forming amyl nitrite.
A method for the administration of amyl nitrite comprising:
- supplying a first sealed compartment which contains amyl alcohol (C5H11OH), a second sealed compartment which contains nitrite of the formula MNO2 in an aqueous medium wherein M represents a metal cation selected from an alkali metal or alkali earth metal;
- and a third sealed compartment which contains an acidic cationic exchange resin;
- wherein said first and second sealed compartments are opened and said amyl alcohol and said nitrite are introduced into said third sealed compartment and said amyl alcohol is converted to amyl nitrite (C5H11ONO).
A device for the delivery of amyl nitrite comprising:
- a. a first sealed compartment containing which contains amyl alcohol (C5H11OH)
- b. a second sealed compartment which contains nitrite of the formula MNO2 in an aqueous medium wherein M represents a metal cation selected from an alkali metal or alkali earth metal;
- and
- c. a third sealed compartment which contains an acidic cationic exchange resin.
1 more element
Dependencies are inferred from the claim text.