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US 2015/0105466 A1Published application
Intrathecal baclofen pharmaceutical dosage forms with fewer degradation products
AssigneeMallinckrodt Inc.
InventorsJohn J. Foster, Angela A. Strantz
Life of this patent
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Abstract
The present invention relates generally to a sterile, particulate-free, stable intrathecal baclofen solution with less than 0.5% of 4-(4-chlorophenyl)-2-pyrrolidone, a degradation product. These solutions are stable under a variety of storage conditions and for extended periods of time. Also disclosed are methods for preparing such compositions.
Claims20
A sterile aqueous solution of baclofen containing 0.5% or less (by weight of baclofen) of 4-(4-chlorophenyl)-2-pyrrolidone.
Dependencies are inferred from the claim text.