In vitro method for predicting disease outcome in stage ii colorectal cancer
AssigneeUniversiteit Maastricht
InventorsManon van Engeland, Adriaan Pieter de Bruïne, James Herman
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Abstract
The present invention relates to a method for determining the likelihood of disease outcome of a patient diagnosed with microsatellite stable, stage II colorectal cancer. More in particular, the present invention relates to a method for determining the prognosis of a patient diagnosed with microsatellite stable, stage II colorectal cancer wherein the CpG island methylation status of the promoter of the CHFR gene is determined and wherein methylation of the promoter is indicative of a poor prognosis.
Claims7
A method for determining the prognosis of a subject diagnosed with microsatellite stable, stage II colorectal cancer, the method comprising:
- determining the CpG island methylation status of the promoter of the CHFR gene in the cancer, wherein methylation of the promoter is indicative of a poor prognosis.
Dependencies are inferred from the claim text.