Biomarkers for increased risk of drug-induced acute hypersensitivity syndrome
AssigneeSevere Adverse Event (Sae) Consortium
InventorAris FLORATOS
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Abstract
The present disclosure provides a method for predicting the risk of a patient for developing adverse drug reactions, particularly drug-induced acute hypersensitivity syndrome (AHSS). The disclosure also provides a method of identifying a subject afflicted with, or at risk of, developing AHSS. In some aspects, the methods comprise analyzing at least one genetic marker, wherein the presence of the at least one genetic marker indicates that the subject is afflicted with, or at risk of, developing AHSS.
Claims2
A method of identifying a subject afflicted with, or at risk of, developing acute hypersensitivity syndrome (AHSS), the method comprising:
- (a) obtaining a nucleic acid-containing sample from the subject;
- and
- (b) analyzing the sample to detect the presence of at least one genetic marker, wherein the presence of the at least one genetic marker indicates that the subject is afflicted with, or at risk of, developing AHSS.
Dependencies are inferred from the claim text.