US 2015/0104531 A1Published application

Trans-aconitic acid compounds and uses thereof for inhibiting phosphodiesterase 7

AssigneeAcademia Sinica

InventorsShui-Tein CHEN, I-Shu LEE, Yu-Chun CHEN

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Abstract

Methods of inhibiting a phosphodiesterase (PDE) 7 enzyme such as PDE7A1 and methods for treating diseases associated with PDE7 using one or more trans-aconitic acid compounds, which can be isolated from plants.

Claims15

Dependent claims

A method for inhibiting a phosphodiesterase 7 (PDE7), comprising:

contacting a PDE7 with a composition comprising a trans-aconitic acid compound in an amount effective in inhibiting the activity of a PDE7.

Dependencies are inferred from the claim text.

Facts

Application: 14/513,029Filed 13 Oct 2014
Priority: 11 Oct 2013
Published: 16 Apr 2015
Term ends: Not estimatedThe source records don’t support an estimate.

Classification15 codes

A61K 31/194
Carboxylic acids, e.g. valproic acid: having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
A61K 36/899
Liliopsida: poaceae or Gramineae , e.g. bamboo, corn or sugar cane
A61K 36/8998
Poaceae or Gramineae , e.g. bamboo, corn or sugar cane: hordeum
A61K 36/9062
Zingiberaceae: alpinia, e.g. red ginger or galangal

Family

Application61/889,778Us provisional application · filed 11 Oct 2013
US 9,610,268 B2Related patent
US 2015/0104531 A1This patent

From the US filing history. Foreign family members aren’t listed.

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