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US 2015/0104352 A1Published application
Use of disulfide bonds to form a reversible and reusable coating for nanofluidic devices
AssigneeInternational Business Machines Corporation
InventorsNatalie Gunn, Jose M. Lobez Comeras, Priscilla Rogers, John Wagner
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Abstract
A reusable coating for a nanopore structure is disclosed herein. A nanopore structure includes a substrate comprising a nanochannel and a monolayer of a chemical compound disposed onto at least a portion of a surface of the nanochannel. The chemical compound forms a reversible bond with at least one analyte binding compound introduced into the nanochannel. Methods for making and using the reusable coating are also disclosed.
Claims11
A nanopore structure comprising:
- a substrate comprising a nanochannel;
- and
- a monolayer of a chemical compound disposed onto at least a portion of a surface of the nanochannel, wherein the chemical compound forms a reversible bond with at least one analyte binding compound introduced into the nanochannel.
11-20. (canceled)
Dependencies are inferred from the claim text.