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US 2015/0087840 A1Published application
Process for Manufacturing Naphthyridine Derivatives
AssigneeActelion Pharmaceuticals Ltd.
InventorsStefan Abele, Hans Meier, Gunther Schmidt, Heinz Steiner
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Abstract
The invention relates to a new process suitable for manufacturing the compounds of formula I (I) wherein W is H, Br, Cl or methyl, which are synthetic intermediates useful in the preparation of antibiotic compounds.
Claims15
A method for manufacturing a compound of formula I-2
- comprising reacting a compound of formula (I-1)
- with fluorine gas in the presence of sulfuric acid at a temperature from 20° C. to 100° C.
Dependencies are inferred from the claim text.