Process for the preparation of vilazodone hydrochloride and its amorphous form

A process for preparation of a thermodynamically stable and substantially pure amorphous form of Vilazodone hydrochloride, which comprises:

• a) providing a solution of Vilazodone hydrochloride in a first solvent or a mixture of solvents;
• b) optionally, filtering said solvent solution to remove any extraneous matter;
• and
• c) substantially removing said solvent from said solvent solution to afford amorphous form of Vilazodone hydrochloride.

A process for the preparation of Vilazodone or a salt thereof and its amorphous form, comprising:

• a. reacting 5-nitro salicaldehyde of formula (III) with 2-bromo diethyl malonate of formula (IV) to get compound of formula (V);
• b. reducing compound of formula (V) to get compound of formula (VI);
• c. converting compound of formula (VI) to compound of formula (VII);
• d. Condensing compound of formula (VII) or salt thereof with compound of formula (VIII) to get compound of formula (II) or salt thereof;
• e. reacting compound of formula (II) with source of ammonia to get compound of formula (I);
• and
• f. converting Vilazodone base of formula (I) into amorphous form of Vilazodone hydrochloride.