Compositions and methods for reducing or preventing metastasis
AssigneeInfectious Disease Research Institute
InventorsShamgar BEN-ELIYAHU, Pini MATZNER, Steven G. REED
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Abstract
Compositions comprising glucopyranosyl lipid adjuvant (GLA) and methods for reducing or preventing the formation of cancer metastasis utilizing same are provided. The compositions may be formulated for local-regional delivery. The compositions may be substantially devoid of a cancer antigen. The treatment with GLA may be combined with treatment with a COX2 inhibitor and a beta-adrenergic blocker.
Claims33
A method for reducing or preventing metastasis development in a subject, the method comprising the step of administering to the subject a pharmaceutical composition comprising glucopyranosyl lipid adjuvant (GLA) or a pharmaceutically acceptable salt thereof as an active ingredient, wherein said administration is effective in reducing or preventing metastasis.
A pharmaceutical composition comprising GLA or a pharmaceutically acceptable salt thereof as an active ingredient, for use in the reduction or prevention of metastasis development, said composition being substantially devoid of a cancer antigen.
Dependencies are inferred from the claim text.