US 2015/0086540 A1Published application

Methods of using an antibody to inhibit WNT-mediated cardiac remodeling

AssigneeVanderbilt University

InventorsEthan LEE, Pampee P. YOUNG, Josiane EID

Life of this patent

Estimating the term…

Abstract

The present invention is directed to monoclonal antibodies and fragments thereof directed to LRP5/6 that find use in the prevention and treatment of cardiac remodeling and cancer. Also disclosed are methods for using such monoclonal antibodies in the prevention and treatment of such diseases.

Claims21

Dependent claims

1-20. (canceled)

Dependencies are inferred from the claim text.

Facts

Application: 14/446,073Filed 29 Jul 2014
Priority: 28 Apr 2011
Published: 26 Mar 2015
Term ends: Not estimatedThe source records don’t support an estimate.

Classification19 codes

C07K 16/30
Against receptors, cell surface antigens or cell surface determinants: from tumour cells
A61K 39/3955
Against materials from animals: against proteinaceous materials, e.g. enzymes, hormones, lymphokines
A61K 39/39558
Against materials from animals: against tumor tissues, cells, antigens
A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…

Family

Application61/480,218Us provisional application · filed 28 Apr 2011
Application13/460,242Continuation · filed 30 Apr 2012
Application14/446,073Continuation
US 2012/0276089 A1Published application
US 8,790,650 B2Related patent
US 9,175,090 B2Related patent
US 2015/0086540 A1This patent

From the US filing history. Foreign family members aren’t listed.

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