US 2015/0085275 A1 · PHOTOMETRIC DEVICE AND METHOD

Abstract

Disclosed are methods and devices for photometric measurements of a liquid sample. The methods and devices use one or more diffractive reflective surfaces to enable a light beam incident on a measurement chamber to be steered so as to be reflected inside the measurement chamber to achieve relatively long optical paths in the measurement chamber. The liquid sample may be blood or blood serum. The measurement chamber may be provided in a microfluidic device, for example a centrifugal microfluidic device. Some embodiments enable multiplexing of different wavelengths or path lengths. Some embodiments make use of multiple returned beams to determine the position and/or orientation of the measurement chamber.

Claims21

Dependent claims

A method of deriving a. photometric measure of a liquid disposed in a chamber between first and second chamber walls, the second chamber wall comprising one or more diffractive reflective surfaces, the method comprising:

directing a first light beam having a first wavelength through the first wall and liquid to a first location on the one or more diffractive reflective surfaces to cause the first light beam to be diffracted such that a first selected order beam of a first selected diffraction order is reflected at or in the first wall towards the second wall, the reflected first selected order beam being diffracted at a second location on the one or more diffractive reflective surfaces such that a first other order beam of a first other diffraction order, different from the first selected diffraction order, exits the chamber through the first wall;
detecting the first other order beam to derive a first signal relating to the first other order beam;
and
deriving the photometric measure using the first signal,

1 more element

Dependencies are inferred from the claim text.

Photometric device and method

Life of this patent

Photometric device and method

Life of this patent

Abstract

Claims21