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AssigneeMerck Sharp & Dohme Corp.
InventorsIan M. Bell, Mark E. Fraley, Steven N. Gallicchio, Anthony Ginnetti, Helen J. Mitchell, Daniel V. Paone, Donnette D. Staas, Cheng Wang, C. Blair Zartman, Heather E. Stevenson
Estimating the term…
The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
A compound of Formula I:
2-14. (canceled)
A pharmaceutical composition which comprises an inert carrier and a compound of claim 2, or a pharmaceutically acceptable salt thereof.
A method of treating headache in a mammalian patient in need of such treatment, which comprises administering to the patient a therapeutically effective amount of a compound of claim 2, or a pharmaceutically acceptable salt thereof.
18-20. (canceled)
Dependencies are inferred from the claim text.