s-TRIAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME

A s-triazine compound having a formula:

• wherein
• each L1 and L2 is independently selected from a single bond, or C1-C4 alkylene;
• L3 is selected from C2-C6 alkylene, C2-C6 alkenyl, and C2-C6 alkynyl;
• each R1 and R2 is independently selected from hydrogen, and substituted or unsubstituted C1-C6 alkyl;
• or
• R1 and R2 may join together to form a 4-7 membered heterocycloalkyl;
• or
• R1 is H;
• and R2 is —C(═NH)—NH2;
• R3 is R4;
• or R3 is selected from substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl;
• R4 is substituted or unsubstituted
• each X is C or N;
• provided that no more than three Xs are N at one time;
• each Y is C or N;
• provided that no more than three Ys are N at one time;
• R6 is H or substituted or unsubstituted C1-C6 alkyl;
• each R5a, R5b, or R5c is independently H or substituted or unsubstituted C1-C6 alkyl;
• or a pharmaceutically acceptable salt, solvate or prodrug thereof;
• and stereoisomers, isotopic variants and tautomers thereof.