Enhanced functionality and delivery of a protein from a porous substrate
AssigneeBio-Rad Laboratories, Inc.
InventorsClayton T. McKee, William Strong
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Abstract
Compositions, methods, articles of manufacture, and kits are provided for storage and delivery of proteins.
Claims72
A method of delivering a protein, the method comprising:
- providing a porous substrate comprising a reversibly immobilized protein and a protein aggregation modifying agent;
- and
- eluting the reversibly immobilized protein from the porous substrate with an eluent,
- thereby delivering the protein.
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A method of storing a protein the method comprising:
- providing a porous substrate and a protein aggregation modifying agent;
- contacting the porous substrate in the presence of the protein aggregation modifying agent with a solution containing a protein;
- and
- reversibly immobilizing the protein on the porous substrate,
- thereby storing the reversibly immobilized protein on the porous substrate.
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Dependencies are inferred from the claim text.