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US 2015/0030575 A1Published application
Orally administered plastid expressed cholera toxin b subunit-exendin 4 as treatment for type 2 diabetes
AssigneeUniversity of Central Florida Research Foundation, Inc.
InventorHenry Daniell
Life of this patent
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Abstract
Disclosed herein are compositions and methods for treating Type II diabetes. The compositions comprise plant expressed Exendin 4. Particularly exemplified are plant derived compositions that include a CTB-EX4 conjugate that is bioencapsulated in chloroplasts.
Claims23
1-34. (canceled)
A plant plastid comprising a plastid genome transformed with a heterologous DNA coding sequence encoding at least one fusion protein selected from the group consisting of CTB-Exendin, said coding sequence being integrated into said plastid genome such that said CTB-Exendin is expressed in and present in said plastid.
Dependencies are inferred from the claim text.