System and method for correcting for image artifacts in x-ray image data

One or more non-transitory computer-readable media encoding one or more processor-executable routines, wherein the one or more routines, when executed by a processor, cause acts to be performed, comprising:

• dividing pixels of X-ray image data into a plurality of pixel value regions based on a pixel value of each pixel, wherein each pixel value region has a different range of pixel values;
• generating calibrated X-ray image data for each pixel value region, wherein the respective calibrated X-ray image data for each pixel value region is generated using a different dose of radiation;
• calculating a gain slope for each pixel value region based on the calibrated X-ray image data;
• and
• calculating a pixel gain correction for the pixels of the X-ray image data based on at least one of the calculated gain slopes.

An imaging system, comprising:

• a radiation source;
• a digital X-ray detector configured to generate X-ray image data;
• control circuitry configured to acquire the X-ray image data from the digital X-ray detector;
• and
• processing circuitry configured to apply a gain correction to the X-ray image data via a plurality of slope maps, wherein the processing circuitry is configured to generate the slope maps by executing code to perform the acts of:
• dividing pixels of X-ray image data into a plurality of pixel value regions based on a pixel value of each pixel, wherein each pixel value region has a different range of pixel values;
• generating calibrated X-ray image data for each pixel value region, wherein the respective calibrated X-ray image data for each pixel value region is generated using a different dose of radiation;
• and
• calculating a gain slope for each pixel value region based on the calibrated X-ray image data.