Stent formed from crosslinked bioabsorbable polymer
AssigneeAbbott Cardiovascular Systems Inc.
InventorLothar W. Kleiner
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Abstract
A stent having a stent body made from a crosslinked bioabsorbable polymer is disclosed. A method of making the stent including exposing a tube formed from a bioabsorbable polymer to radiation to crosslink the bioabsorbable polymer and forming a stent body from the exposed tube is disclosed. The tube can include a crosslinking agent which induces crosslinking upon radiation exposure. Additionally or alternatively, the bioabsorbable polymer can be a copolymer that crosslinks upon exposure to radiation in the absence of a crosslinking agent.
Claims8
A stent comprising a stent body for supporting a vascular lumen, wherein the stent body comprises a crosslinked bioabsorbable polymer, wherein the crosslinked bioabsorbable polymer is formed through crosslinking of a copolymer of degradable functional groups and highly reactive functional groups, wherein the degradable functional groups are derived from monomers that form a biodegradable polymer, wherein the highly reactive functional groups are derived from a lactone functionalized with an alkene or an alkyne group, wherein the crosslinking is between the degradable functional groups and the highly reactive functional groups.
The stent of claim 8, wherein the degradable functional groups are derived from L-lactic acid.
The stent of claim 8, wherein the degradable functional groups are derived from monomers selected from the group consisting of glycolic acid, caprolactone, dioxanone, D-lactic acid, mandelic acid, trimethylene carbonate, 4-hydroxy butyrate, and butylene succinate.
The stent of claim 8, wherein the lactone is allyl-δ-caprolactone or a-diallyl-δ-caprolactone
The stent of claim 8, wherein the lactone is a-alkyne-δ-valerolactone or a-alkyne-δ-caprolactone.
The stent of claim 8, wherein the copolymer of the form AxBy, wherein A is L-lactic acid and B is an alkene or alkyne copolymerized with A, and wherein x is the mole % of A and y is the mole % of B in the copolymer.
Dependencies are inferred from the claim text.