Use of il-20 antagonists for alleviating obesity
AssigneeNational Cheng Kung University
InventorsMing-Shi Chang, Yu-Hsiang Hsu
Life of this patent
Estimating the term…
Abstract
Alleviating obesity in a subject (e.g., a human subject) having, being suspected of having, or at risk for obesity using an IL-20 antagonist, which can be an antibody that blocks a signaling pathway mediated by IL-20. Such antibodies include anti-IL-20 antibodies and anti-IL-20R antibodies that specifically block the IL-20 signaling pathway.
Claims20
A method for alleviating obesity in a subject, comprising administering to a subject in need thereof an effective amount of an IL-20 antagonist.
A method for suppressing adipocyte differentiation, comprising contacting an effective amount of an IL-20 antagonist with adipocyte precursor cells under conditions, which allow for differentiation of the precursor cells into adipocytes in the absence of the IL-20 antagonist.
Dependencies are inferred from the claim text.