Organic-Inorganic Composite Materials as a Result of Biomineralization
AssigneeLeibniz-Institut fuer Neue Materialien gemeinnuetzige GmbH
InventorsIngrid Weiss, Eva Weber, Magdalena Eder, Eduard Arzt, Andreas Simon Schneider
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Abstract
A method for producing organic-inorganic composite materials includes at least one biomineralising protein and/or polypeptide-encoding recombinant polynucleotide being introduced into at least one host cell, preferably from the class of slime moulds, and the expressed protein and/or polypeptide influencing the formation of inorganic particles in an extracellular matrix of the host cell.
Claims14
A method of identifying biomineralizing systems, comprising:
- a) introducing at least one recombinant polynucleotide into at least one host cell, said recombinant polynucleotide;
- a1) encoding at least one protein and/or polypeptide, and
- a2) being suitable for expressing the encoded protein and/or polypeptide in said host cell,
- b) expressing the protein encoded by the recombinant polynucleotide;
- and
- c) investigating a biomineralizing action of the expressed protein.
A recombinant nucleic acid, comprising a recombinant nucleic acid that encodes a fusion protein comprising at least one protein and/or polypeptide with biomineralizing action and at least one amino acid sequence for influencing secretion of said fusion protein, and includes a corresponding promoter.
A recombinant protein and/or polypeptide, comprising a fusion protein of at least one protein and/or polypeptide with biomineralizing action and an amino acid sequence for influencing secretion of said fusion protein, and said protein and/or polypeptide with biomineralizing action has a sequence which is at least 80% homologous to that of a protein and/or polypeptide from table 2.
Dependencies are inferred from the claim text.