Staples, staplers, anastomosis devices, and methods for their applications

A device for applying staples to a tissue, comprising:

• a cartridge, adapted for receiving at least one stapling element, said stapling element comprising:
• a first shape, while maintained within a lumen of the cartridge, comprising an elongated body, with a tapered end, said elongated body having a cross section which does not match a cross section of said cartridge, for preventing said stapling element from rotating, when in said cartridge, thus maintaining a predetermined closing direction;
• and
• a second shape, assumed when said stapling element issues from said cartridge and is inserted into the tissue, said second shape being designed to close into a loop, for forming a staple in the tissue,
• wherein said cartridge is adapted for maintaining said at least one stapling element at a fixed orientation, with respect to a direction of closing of said stapling element;
• a mechanism, in mechanical communication with said cartridge, for issuing said at least one stapling element from said cartridge;
• and
• a proximal end, with respect to said tissue, having a rigid, proximal-end frame, which defines an opening from which said at least one stapling elements issues.

A device for applying staples to a tissue, comprising:

• a cartridge, adapted for storing at least one stapling element, in a coiled position, each said stapling element having a tapered portion, forming a sharp, pointed edge, at a proximal end, with respect to the tissue, for piercing the tissue;
• a mechanism, in mechanical communication with said at least one stapling element, for issuing said at least one stapling element from said cartridge;
• and
• a proximal end, with respect to said tissue, having a rigid, proximal-end frame, which defines an opening from which said at least one stapling element issues.