Apparatus and method for optimizing treatment using medication compliance patterns and glucose sensor

A method of optimizing treatment of a medication recipient patient, comprising:

• generating usage data regarding a patient's compliance with a medication treatment regimen with a medication monitor;
• providing the usage data to a central server over a predetermined period of time;
• determining the patient's pattern of compliance with the medication treatment regimen;
• collecting a biological sample with a detection device that is operatively connected to the medication monitor;
• sensing a target agent with a target agent sensor provided with the detection device, the sensor comprising:
• a solid support to which is attached a recognition molecule that permits detection of the target agent, wherein the recognition molecule specifically binds to the target agent in the presence of fee target agent but not significantly to other agents;
• a substance that can be enzymatically converted to glucose;
• an enzyme that can catalyze the conversion of fee substance to glucose in the presence of the target agent;
• and
• detecting the glucose produced from the substance with a glucose meter to generate medication data, wherein
• the detection of glucose indicates a presence of the target agent in the biological sample, and an absence of detected glucose indicates an absence of the target agent in the biological sample;
• correlating the patient's pattern of compliance with the medication data;
• and
• outputting at least one recommendation selected from the group consisting of:
• replacing at least one medication used in the treatment regimen with at least one different medication, changing at least one dosage of at least one medication used in the treatment regimen, changing the tuning of recommended usage of at least one medication in the treatment regimen, and not changing the treatment regimen.

A self-contained medication monitor comprising:

• a housing body configured to contain medication;
• a first detection device for detecting removal of medication from the self-contained medication monitor;
• a second detection device having a target agent sensor for detecting a target agent in a biological sample from a user, wherein
• the target agent sensor comprises:
• a solid support to which is attached a recognition molecule that specifically binds to the target agent in the presence of the target agent but not significantly to other agents;
• a substance that can be enzymatically converted to glucose;
• and
• an enzyme that can catalyze the conversion of the substance to glucose in the presence of the target agent;
• a processor that produces medication usage data and medication data based on detected removal of the medication and an amount of glucose sensed and that outputs recommendations to the patient based on the medication usage data and medication data;
• and
• a display device configured to display the recommendations to the patient.