Drug delivery devices with drug-permeable component and methods
AssigneeTARIS Biomedical LLC
InventorsHeejin Lee, Karen Daniel, Matthew Sansone
Life of this patent
Estimating the term…
Abstract
Implantable drug delivery devices include a housing having a closed drug reservoir lumen bounded by a first wall structure and a hydrophilic second wall structure, and a drug contained in the drug reservoir lumen, wherein the first wall structure is impermeable to the drug and the second wall structure is permeable to the drug. Methods of providing controlled release of drug to a patient include deploying a drug delivery device in the patient releasing a drug from the drug reservoir lumen via diffusion through the second wall structure.
Claims21
An implantable drug delivery device comprising:
- a housing having a closed drug reservoir lumen bounded by a first wall structure and a hydrophilic second wall structure;
- and
- a drug contained in the drug reservoir lumen,
- wherein the first wall structure is impermeable to the drug, and the second wall structure is permeable to the drug, and
- wherein:
- (i) the first wall structure is a cylindrical tube and the second wall structure is an end wall disposed at at least one end of the cylindrical tube, or
- (ii) the first wall structure and the second wall structure are adjacent one another and together form a cylindrical tube.
A method of providing controlled release of drug to a patient, comprising:
- deploying a drug delivery device in the patient, the device comprising a closed drug reservoir lumen bounded by a first wall structure and a hydrophilic second wall structure;
- and
- releasing a drug from the drug reservoir lumen via diffusion through the second wall structure,
- wherein the first wall structure is impermeable to the drug, and the second wall structure is permeable to the drug, and
- wherein:
- (i) the first wall structure is a cylindrical tube and the second wall structure is an end wall disposed at at least one end of the cylindrical tube, or
- (ii) the first wall structure and the second wall structure are adjacent one another and together form a cylindrical tube.
Dependencies are inferred from the claim text.