Detection of infusion pump conditions

A computer implemented method of monitoring an ambulatory infusion device, the ambulatory infusion device comprising:

• an infusion cartridge, the infusion cartridge including a collapsible reservoir for containing a fluid and a substantially rigid shell disposed over the collapsible reservoir and forming an interior volume between an outside surface of the collapsible reservoir and an inside surface of the shell;
• a pump device configured to selectively receive the infusion cartridge and cooperate with the infusion cartridge to deliver fluid from the reservoir to the patient;
• a pressure sensor located in one of the infusion cartridge and the pump, the pressure sensor in communication with the interior volume of the infusion cartridge;
• and
• a processor located in one of the infusion cartridge and the pump, the method comprising:
• actuating the pressure sensor to take pressure measurements at regular time intervals;
• periodically assessing a preselected number of the pressure measurements with statistical analysis to identify statistical measures associated with the pressure measurements;
• and
• using the statistical measures to assess the status of the flexible reservoir and the pump device.