Pharmaceutical compositions comprising modified fucans and methods relating thereto
AssigneeARC Medical Devices Inc.
InventorChristopher Michael Kevin Springate
Life of this patent
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Abstract
Compositions and methods relating to fucan agents useful for the treatment, prevention, inhibition, etc., of fibrous adhesions or other diseases.
Claims23
-27. (canceled)
A method of inhibiting a fibrous adhesion in an animal comprising administering a therapeutically effective amount of a medical composition comprising a therapeutically effective amount of a fucan in combination with at least one pharmaceutically acceptable excipient, filler, carrier or diluent, wherein the fucan has a sulphate content between about 14 to 40% w/w;
- a total carbohydrate content between about 37 to 75% w/w;
- a fucose content as a percentage of total carbohydrate content of between about 31 to 71%;
- an acetyl content as a ratio of acetyl:fucose of between about 0 to 20% w/w;
- a protein content of about 0 to 12% w/w;
- an appearance of white, off-white, light yellow, light orange, light green or light brown;
- and when made up to a 0.1% w/v solution results in a solution with a pH of about 4 to 8.
A method of inhibiting a fibrous adhesion in an animal comprising administering a therapeutically effective amount of a composition comprising a therapeutically effective amount of a fucan in combination with at least one pharmaceutically acceptable excipient, filler, carrier or diluent, wherein the fucan has a sulphate content of between about 14 to 40% w/w;
- a total carbohydrate content of between about 37 to 75% w/w;
- a fucose content as a percentage of total carbohydrate content of between about 70 to 100%;
- an acetyl content as a ratio of acetyl:fucose of between about 0 to 20% w/w;
- a protein content of about 0 to 12% w/w;
- an appearance of white, off-white, light yellow, light orange, light green or light brown;
- and when made up to a 0.1% w/v solution results in a solution with a pH of about 4 to 8.
Dependencies are inferred from the claim text.