Droplet generator with collection tube

A system for forming a plurality of sample-containing droplets suspended in a background fluid, comprising:

• a droplet generation component including:
• a plurality of sample wells, background fluid wells, and droplet outlet regions all integrally formed with a substrate;
• a network of channels formed in the substrate and fluidically interconnecting each sample well with a corresponding background fluid well and a corresponding droplet outlet region;
• and
• a plurality of droplet generation regions, each configured to generate sample-containing droplets suspended in the background fluid, and each defined by the intersection of a first channel configured to transport sample-containing fluid from one of the sample wells to the droplet generation region, a second channel configured to transport background fluid from the corresponding background fluid well to the droplet generation region, and a third channel configured to transport sample-containing droplets from the droplet generation region to the corresponding droplet outlet region;
• and
• a droplet reservoir component including a plurality of interconnected reservoirs, each one of the reservoirs being configured to attach securely to, to be removable from, and to receive sample-containing droplets from, a respective one of the droplet outlet regions;
• wherein each droplet outlet region includes an aperture allowing sample-containing droplets to pass from the droplet outlet region through a bottom surface of the substrate to a respective one of the reservoirs.