Kinetin/zeatin topical formulation
AssigneeDow Pharmaceutical Sciences, Inc.
InventorsPramod Sarpotdar, Sarmistha Basu, Varsha D. Bhatt, Yunik Chang, Gordon J. Dow
Life of this patent
Estimating the term…
Abstract
The solubility of kinetin and/or of zeatin is increased when either or both are combined in a formulation that includes a polyoxyalkylene-n-glycerol dicarboxylate component and a fatty acid component. These two components provide a synergistic increase in the solubility of kinetin and/or zeatin that is greater than that which would be expected based on the solubility of kinetin and zeatin in the individual components.
Claims13
A method for increasing the solubility of kinetin and/or zeatin comprising combining the kinetin and/or zeatin in a formulation that includes a polyoxyalkylene-n-glycerol dicarboxylate component and a fatty acid component, wherein the amounts of the polyoxyalkylene-n-glycerol dicarboxylate and the fatty acid are sufficient to provide a synergistic increase in the solubility of the kinetin and/or the zeatin in the formulation.
A formulation comprising kinetin and/or zeatin in which the kinetin and/or zeatin is contained as part of a liposome and wherein the kinetin and zeatin do not precipitate from the formulation in the presence of water.
Dependencies are inferred from the claim text.