Nutritional Compositions Containing a Peptide Component and Uses Thereof

A nutritional composition, comprising:

• (i) a carbohydrate source;
• (ii) a fat source;
• and
• (iii) a protein equivalent source;
• wherein
• a) 20% to 80% of the protein equivalent source includes a peptide component comprising at least 5 peptides selected from Table 1 and at least 3 additional peptides selected from Table 2;
• and
• b) 20% to 80% of the protein equivalent source comprises an intact protein, a partially hydrolyzed protein, or combinations thereof.

A method for reducing the incidence of autoimmune disease, comprising providing to the subject, a nutritional composition comprising:

• a carbohydrate source,
• a fat source, and
• a protein equivalent source,
• wherein 20% to 80% of the protein equivalent source includes a peptide component comprising SEQ ID NO 4, SEQ ID NO 13, SEQ ID NO 17, SEQ ID NO 21, SEQ ID NO 24, SEQ ID NO 30, SEQ ID NO 31, SEQ ID NO 32, SEQ ID NO 51, SEQ ID NO 57, SEQ ID NO 60, and SEQ ID NO 63;
• and wherein 20% to 80% of the protein equivalent source comprises intact protein, partially hydrolyzed protein or combinations thereof.