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US 2014/0271528 A1Published application
Solid polyglycol-based biocompatible pre-formulation
AssigneeMedicus Biosciences, LLC
InventorsSyed H. ASKARI, Yeon S. CHOI, Paul YuJen WAN
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Abstract
Provided herein are pre-formulations forming a biocompatible hydrogel polymer comprising at least one nucleophilic compound or monomer unit, at least one electrophilic compound or monomer unit, and optionally a therapeutic agent and/or viscosity enhancer. In some embodiments, the biocompatible hydrogel polymer covers a wound in a mammal and adheres to the surrounding skin tissue. In other embodiments, the hydrogel polymer is delivered into a joint space to treat joint disease or navicular disease.
Claims20
A solid polyglycol-based, fully synthetic, pre-formulation, comprising:
- (a) at least one solid first compound comprising more than two nucleophilic groups;
- and
- (b) at least one solid second compound comprising more than two electrophilic groups wherein the solid polyglycol-based, fully synthetic, pre-formulation polymerizes and/or gels to form a polyglycol-based, fully synthetic, biocompatible hydrogel polymer after addition of a liquid component.
Dependencies are inferred from the claim text.